CBD for Focus and Concentration + 7 more amazing uses!
Cannabis is one of the most ancient non-food crops cultivated by humans. It has been used in the Traditional Medicines of South Africa, South America, Turkey, Egypt and many regions of Asia.1 Only two to three generations ago, Cannabis was routinely used in Europe and the USA to treat a variety of conditions, from migraines to nausea to Parkinson’s disease.2 Let’s take a closer look at what CBD (a constituent of cannabis) can be used for today.
What is CBD?
The Cannabis sativa (hemp) plant contains over 500 known compounds.3 The most well-known group of these compounds are the phytocannabinoids, of which there are over 100 different types. These phytocannabinoids can broadly be divided into:
- Psychoactive compounds, such as Tetrahydrocannabinol (THC)
- Non-psychoactive compounds, including Cannabidiol (CBD), Cannabigerol (CBG) and other plant chemicals such as Cannabis terpenes.4
Cannabidiol (CBD) is a non-psychoactive cannabinoid found in cannabis.
How do phytocannabinoids work?
The phytocannabinoids all have an effect on the body’s own cannabinoid system, binding to the Endocannabinoid receptors found throughout the body.5 The actions of CBD and CBG include:1
- Neuroprotection (protecting nerves against damage) via anti-oxidant, anti-inflammatory, and immune mechanisms1,6 as well as increasing glucose uptake by the neurons.7
- Immune support
- Reduction of the effects of stress8
- Anti-anxiety effects9
- Sleep induction10
Plant terpenes have diverse effects11 including:
- Immune enhancing
- Inhibition of the breakdown of Acetylcholine – pivotal to focus, learning and memory
The cannabinoids and other plant compounds such as the terpenes work synergistically together in the plant and when consumed by humans.4 It has been established that coadministration of CBD and THC can reduce unwanted effects of THC.1
Since Raphael Mechoulam first isolated and synthesized THC in 1964, cannabis research has primarily focused on THC.4 In the last decade there has been increased interest in other phytocannabinoids, especially regarding their antioxidant, anti-inflammatory, anti-anxiety, analgesic and neuroprotective effects. However, the research is relatively new and there is still a lot to learn. In fact, research on CBD, CBG and cannabis terpenes as nootropics is yet to be done. Unfortunately the negative stigma and controversy around cannabis has limited research.1 However, from the little research we do have, the uses and benefits of CBD and other phytocannabinoids look promising!
CBD for focus and concentration
Being able to focus and concentrate is part of our daily lives. The inability to focus or concentrate so can be incredibly frustrating and discouraging. While more scientific research and evidence is needed, many citizen scientists have reportedly been using CBD for focus and concentration with great results.
CBD for sleep and energy
Our energy levels are affected by many things, including our quality of sleep. Research on cannabinoids and sleep is in its infancy and studies in this area are limited by various factors, however, low doses of CBD have been shown to be stimulating.10 In one study, CBD administered in a 1:1 ratio counteracted the sedative effect of THC, thereby demonstrating CBD’s impact on wakefulness.10 In contrast, medium to high dose CBD is sedating and has been examined in the context of treating a number of sleep disorders, including insomnia.10 Another study indicates that phytocannabinoids may increase energy expenditure.4 This means CBD is likely to be useful for staying awake, as well as getting a good night’s sleep – both of which will improve your focus and energy the next day. Although further research is needed, a theoretical connection between cannabinoids and sleep has been demonstrated.10
CBD for anxiety and stress
CBD is likely to improve brain health by decreasing anxiety as well as supporting a healthy stress response. CBD has anxiolytic properties, which means it can assist in relieving the anxiety caused by stress.4,15 CBD may also be beneficial for social anxiety disorder (SAD), post-traumatic stress disorder (PTSD) and anxiety-induced insomnia.4 Symptoms of stress (such as muscular tension, restlessness, fatigue and difficulty concentrating) may also be relieved by CBD. Stress is known to produce rapid changes in endocannabinoid signaling, and in response, the endocannabinoid system can downregulate this activity in stress-responsive brain regions.8 Enhancing cannabinoids signaling prevents the effects of acute stress on emotional memory.8
CBD for pain
CBD has analgesic and anti-inflammatory properties that assist with relieving pain caused by inflammation and tissue, muscle, joint or nerve damage.4,6,15
CBD for neurodegenerative diseases
Cannabinoid extracts are prescribed in patients with glaucoma, in the control of chemotherapy-related vomiting and nausea, and for appetite stimulation in patients with anorexia-cachexia syndrome by HIV.1 CBD and THC appear to have the potential to help treat disorders of the central nervous system such as Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis and Epilepsy, although more human clinical trials are needed.1
Bonus: CBD for memory
CBD may also boost memory!1, 11
Safety and side effects of CBD
CBD (without THC) is considered safe for human consumption and is well tolerated.13 However, CBD might interact with certain medications. Always consult a physician before using any product that contains CBD or other cannabinoids.
Products containing CBD come in various shapes, forms, sizes and doses. From capsules to drops to gummies, there are lots of options to choose from.
Common CBD terms
While shopping for CBD products, you may come across some of the following terms:
Terpenes are the compounds responsible for the flavor and aroma.4 It is believed that terpenes enhance the benefits of other phytocannabinoids.
CBD isolate is typically harvested from Cannabis sativa, this is pure CBD, without any other cannabinoids or terpenes.14
Full-spectrum CBD contains all extracts of the plant, including THC (up to 0.3%), CBD, terpenes, flavonoids, essential oils, and other cannabinoids.14
Broad-spectrum CBD is similar to full spectrum, except that it contains zero or trace amounts of THC.14 Broad-spectrum products may have a higher likelihood of producing beneficial health effects than CBD isolate because of the entourage effect.14
How we formulated Nucleus Alpha
Nucleus Alpha is the foundation of our Nucleus stack, which is the ultimate in high-performance, functional nootropic formulations. CBD-based Nucleus Alpha provides an incredible, jitter-free boost. It is perfect for enhancing focus, concentration and working memory involved in reasoning and decision making. Alpha leverages the benefits of some of the most highly regarded plants and natural compounds so you can perform at your very best.
Nucleus Alpha uses the THC-free cannabinoids, CBD and CBG, as well as cannabis terpenes in a synergistic mix. The carefully chosen cannabinoids work synergistically together, providing clear, calm focus and supporting learning and memory. It also contains a few other thoughtfully selected ingredients. Caffeine is a well-known nootropic, especially when combined with L-Theanine giving you vigor and calm focus. Cordyceps improves energy, focus, learning and memory, and protects nerve cells from damage. GABA provides a calm focus for the stress of mental tasks. Ginkgo supports working memory, which is involved in reasoning and decision making, improves attention and the retrieval of learned facts. Gotu Kola has long been used as a general health tonic. It improves working memory (involved in reasoning and decision making), improves mood, calms anger, decreases anxiety and improves alertness. Lemon Balm has been said to “completely revivify a man”. It Improves cognitive performance and mood, improves working memory and mathematical processing and decreases stress. Lion’s Mane has long been used to improve vigor and strength. It improves both physical and cognitive performance. Vitamin B3 is essential to the function of all cells. It has been used in orthomolecular medicine as a calming agent, improving focus without decreasing cognitive function. Vitamin D3 and K2 work synergistically together supporting brain health. Vitamin D protects nerve cells and is critical to the formation of neurotransmitters, the chemical signals that make the brain work. Vitamin K2 supports overall brain function via it’s anti-oxidant, anti-inflammatory effects and via its roles cell membrane metabolism.
Nucleus Alpha details
We formulated Nucleus Alpha to enhance brain function, facilitate clearer thinking, improve reaction time, reduce fatigue, reduce stress, regulate pain, and sharpen focus.* Nucleus Alpha is water-soluble, which means improved absorption that’s fast-acting with better results. It is THC free, which means zero THC or high feeling – it simply contains non-psychoactive cannabinoids (CBD) for a calm, clear mind. It is manufactured in California and contains no pesticides, heavy metals or molds, according to our COA. Nootropic supplements are an effective and proven alternative to energy drinks, so you are able to focus intensely without the jitters. All of our dietary supplements are made using prebiotic capsule, which stimulate the growth of beneficial gut bacteria. We also use dark bottles to help prevent light-induced degradation, in an effort to provide you with the highest quality products.
Not tested on animals
How to take Nucleus Alpha
We suggest taking Nucleus Alpha upon rising. The caffeine and L-Theanine set you up for the day, immediately focusing you on the task at hand. You get extra support from the other nootropics in this formula, keeping your concentration targeted. We then recommend taking Nucleus Beta and Gamma four hours later to create the ultimate stack. The Citicoline (Choline L-Bitartrate) in Beta is a precursor for Acetylcholine and the Anirecetam in Gamma enhances the Acetylcholine system in the brain. Acetylcholine is essential for brain functioning, including focus and speed of learning. This stack can be repeated three to four hours later if necessary.
CBD and the law
The legality of cannabis for medical and recreational use varies by state, mostly because of the psychoactive chemical tetrahydrocannabinol (THC). In short, CBD is legal under federal law depending on where the CBD is derived from and what it will be added to. If the CBD is sourced from the hemp plant and if it meets certain requirements, it is legal under federal law. At the state level, however, policies regarding the medical and recreational use of cannabis vary greatly, and in many states conflict significantly with federal law. Hemp-derived CBD products with less than 0.3% THC are legal on the federal level, but still illegal under some state laws. Unfortunately this is why we are unable to ship some of our products to certain states. Be sure to familiarize yourself with your state’s laws and the laws of any of your travel destinations.
We hope you take full advantage of CBD and all of its uses! Comment below to let us know how it works for you.
1. Giacoppo, S., Mandolino, G., Galuppo, M., Bramanti, P. & Mazzon, E. Cannabinoids: new promising agents in the treatment of neurological diseases. Molecules 19, 18781-18816 (2014).
2. Russo, E.B. History of cannabis and its preparations in saga, science, and sobriquet. Chem Biodivers 4, 1614-1648 (2007).
3. Solymosi, K. & Köfalvi, A. Cannabis: A Treasure Trove or Pandora’s Box? Mini Rev Med Chem 17, 1223-1291 (2017).
4. Russo, E. Taming THC: Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British journal of pharmacology 163, 1344-1364 (2011).
5. Russo, E. & Guy, G.W. A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Med Hypotheses 66, 234-246 (2006).
6. Gugliandolo, A., Pollastro, F., Grassi, G., Bramanti, P. & Mazzon, E. In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid. Int J Mol Sci 19(2018).
7. Köfalvi, A., et al. Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer’s disease. Neuropharmacology 110, 519-529 (2016).
8. Akirav, I. Cannabinoids and glucocorticoids modulate emotional memory after stress. Neuroscience and biobehavioral reviews 37, 2554-2563 (2013).
9. Campos, A.C. & Guimarães, F.S. Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats. Psychopharmacology (Berl) 199, 223-230 (2008).
10. Babson, K.A., Sottile, J. & Morabito, D. Cannabis, Cannabinoids, and Sleep: a Review of the Literature. Curr Psychiatry Rep 19, 23 (2017).
11. Andre, C.M., Hausman, J.F. & Guerriero, G. Cannabis sativa: The Plant of the Thousand and One Molecules. Front Plant Sci 7, 19 (2016).
12. Campos, A.C., Moreira, F.A., Gomes, F.V., Del Bel, E.A. & Guimarães, F.S. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Philos Trans R Soc Lond B Biol Sci 367, 3364-3378 (2012).
13. Iseger, T.A. & Bossong, M.G. A systematic review of the antipsychotic properties of cannabidiol in humans. Schizophrenia research 162, 153-161 (2015).
14. Cather, J.C. & Cather, J.C. Cannabidiol primer for healthcare professionals. Proceedings (Baylor University. Medical Center) 33(3), 376-379. https://doi.org/10.1080/08998280.2020.1775437 (2020).
15. Morales, P., Hurst, D.P. & Reggio, P.H. Molecular Targets of the Phytocannabinoids: A Complex Picture. Prog Chem Org Nat Prod 103, 103–131. https://doi.org/10.1007/978-3-319-45541-9_4 (2017).